Efficacy of zinc carnosine in the treatment of colorectal cancer and its potential in combination with immunotherapy <i>in vivo</i>

Weiwei Tang; Hanyuan Liu; Xiao Li; Theng Choon Ooi; Nor Fadilah Rajab; Hongyong Cao; Razinah Sharif

doi:doi:10.18632/aging.204380

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Research Paper Volume 14, Issue 21 pp 8688—8699

Efficacy of zinc carnosine in the treatment of colorectal cancer and its potential in combination with immunotherapy in vivo

Figure 8. Pattern diagram showing that ZnC slows the progression of CRC by inhibiting the proliferation, invasion and migration and up-regulates PD-L1 expression via inhibiting miR-570. The combination of ZnC and anti-PD1 therapy is beneficial to synergically increase efficacy of anti-tumor in CRC therapy.