Research Paper Volume 17, Issue 2 pp 365—392
Mitochondrial dysfunction, iron accumulation, lipid peroxidation, and inflammasome activation in cellular models derived from patients with multiple sclerosis
Figure 4. Iron accumulation in control (C1, C2) and MS (P1, P2) fibroblasts. (A) Representative images of Prussian Blue staining. Scale bar = 20 μm. (B) Quantification of iron integrated density. (C) Iron content measured by ICP-MS. Data represent the mean ± SD of three independent experiments. ***p-value < 0.0001 between control and MS cells. aaap-value < 0.0001 between untreated and deferiprone-treated P1 cells. a.u.: arbitrary units.