Research Paper Volume 17, Issue 2 pp 524—549

Figure 1. Alpha-diversity is not significantly different with age and mt-haplotype in OKC-HET^B/W rats. Alpha-diversity of the microbiome from adult (9-months) and old (26-months) OKC-HET^B/W rats was measured by the Chao1 and Shannon index. The alpha-diversity is shown for age (A) and mt-haplotype (B) comparisons for male rats; and age (C) and mt-haplotype (D) comparisons for female rats. Age comparisons were made by combining mt-haplotype groups for adult (gray boxes) and old (white boxes) animals. Mt-haplotype comparisons were made between OKC-HET^B (blue boxes) and OKC-HET^W (red boxes) groups. The data were collected from 6 to 10 rats per group, and the box plots display the 1st and 3rd quartiles with a horizontal line at the median. The whiskers display minimum and maximum values. ^◊Values marginally significant by Fisher’s LSD p < 0.05.