Research Paper Volume 17, Issue 2 pp 524—549

Figure 7. Changes in primary, but not secondary bile acids, are dependent on sex and mt-haplotype. Plasma bile acids from male (A) and female (B) OKC-HET^B (blue boxes) and OKC-HET^W (red boxes) adult (9-months) or old (26-months) rats are shown. The box plots display the 1st and 3rd quartiles with the horizontal line for the median, and the whiskers display minimum and maximum values. The data were collected from 6 to 10 rats per group, and significance was defined as FDR ^*q < 0.05 or values marginally significant by Fisher’s LSD ^◊p < 0.05. Abbreviations: TUDCA: tauroursodeoxycholic acid; CA: cholic acid; TCDCA: taurochenodeoxycholic acid; GCA: glycocholic acid; GUDCA: glycoursodeoxycholic acid; LCT: lithocholytaurine; TDCA: taurodeoxycholic acid.