Research Paper Advance Articles
Fisetin ameliorates vascular smooth muscle cell calcification via DUSP1-dependent p38 MAPK inhibition
Figure 9. Effects of fisetin on calcific marker expression in VSMCs during uremic conditions. Relative mRNA expression (n=10) of BMP2 (A), CBFA1 (B), ALPL (C) and CDKN1A (D) in HAoSMCs treated for 24h with 15% normal serum (NS) or uremic serum (US) without and with 1 μM fisetin (Fis). *(p<0.05), **(p<0.01), ***(p<0.001) significant vs. NS group; †(p<0.05) significant vs. respective serum alone group.