Research Paper Advance Articles

Evaluating the nonlinear effects of sleep duration on biological aging across phenotypic, genomic, and epigenomic data

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Figure 3. Results of multivariable linear regressions of PhenoAge acceleration (PhenoAgeAccel), BioAge acceleration (BioAgeAccel), and leukocyte telomere length on sleep duration. Circles denote point estimates. Error bars denote 95% confidence intervals. Regression models adjusted for: age at baseline, sex, the top five genetic principal components, educational qualifications, body mass index, smoking history, drinking history, physical activity status, leucocyte count (for telomere length as an outcome), and histories of cardiovascular diseases, hypertension, and diabetes mellitus.