Research Paper Advance Articles

Figure 3. Deregulated mmu-miR-145a-5p and mmu-miR-27b-3p levels, along with deregulated adipogenic differentiation genes in white adipose tissue (WAT) of Lmna^G609G/G609G mice. (A) qPCR analysis of miR-145-5p and (B) miR-27b-3p, both normalized to U6. (C) mRNA levels of CCAAT/enhancer binding protein-alpha (C/EBPα), (D) peroxisome proliferation-activated receptor gamma PPARγ and (E) fatty acid binding protein 4 (FABP4), all normalized to GAPDH. (A–E) Values are presented as the mean ± SD (n=3); p > 0.05; * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001 (unpaired t-test).