Research Paper Advance Articles
L-β-aminoisobutyric acid (L-BAIBA) in combination with voluntary wheel running exercise enhances musculoskeletal properties in middle-age male mice
Figure 5. Ex vivo muscle fatigue and recovery from fatigue after the three-month intervention period. Fatigue of contractile force in soleus (SOL) muscle at maximal force (A) and submaximal force (B), and in EDL muscle at maximal force (C) and submaximal force (D). ****p<0.0001, **p<0.01 CTRL vs. VWR; †p<0.001 VWR vs. VWR+L-BAIBA; &p<0.05 VWR vs. CTRL+L-BAIBA. Recovery of contractile force after fatigue in soleus muscle at maximal force (E) and submaximal force (F), and in EDL muscle at maximal force (G) and submaximal force (H). Data is expressed as a percentage of initial force at baseline before fatigue. ****p<0.0001, *p<0.05 CTRL vs. VWR; †p<0.01 VWR vs. VWR+L-BAIBA; &p<0.05 VWR vs. CTRL+L-BAIBA, two-way ANOVA with Bonferroni. n = 8 CTRL, n = 9 VWR, n = 8 CTRL+L-BAIBA, n = 8 VWR+L-BAIBA. Mean ± SD.