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Research Paper Volume 13, Issue 17 pp 21451-21469
Identification and epidemiological evaluation of gastric cancer risk factors: based on a field synopsis and meta-analysis in Chinese population
Relevance score: 5.1428895Fujiao Duan, Chunhua Song, Jiachen Shi, Peng Wang, Hua Ye, Liping Dai, Jianying Zhang, Kaijuan Wang
Keywords: gastric cancer, risk factors, genetic variants, susceptibility, field synopsis
Published in Aging on September 6, 2021
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Research Paper Volume 13, Issue 15 pp 19486-19509
A combined hypoxia and immune gene signature for predicting survival and risk stratification in triple-negative breast cancer
Relevance score: 5.275884Xia Yang, Xin Weng, Yajie Yang, Meng Zhang, Yingjie Xiu, Wenfeng Peng, Xuhui Liao, Meiquan Xu, Yanhua Sun, Xia Liu
Keywords: triple-negative breast cancer, risk stratification, hypoxia, immune, survival
Published in Aging on August 2, 2021
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Research Paper Volume 13, Issue 3 pp 3712-3725
Advanced paternal age and risk of cancer in offspring
Relevance score: 5.872444Yangyang Sun, Xu Li, Wei Jiang, Yuanming Fan, Qiong Ouyang, Wei Shao, Raphael N. Alolga, Yuqiu Ge, Gaoxiang Ma
Keywords: paternal age, cancer risk, offspring, cohort study
Published in Aging on December 19, 2020
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Research Paper Volume 12, Issue 22 pp 22869-22891
Global burden and trend of acute lymphoblastic leukemia from 1990 to 2017
Relevance score: 4.151313Ming Yi, Linghui Zhou, Anping Li, Suxia Luo, Kongming Wu
Keywords: global burden of disease, acute lymphoblastic leukemia, cancer statistics, social-demographic index, cancer risk factor
Published in Aging on November 16, 2020
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Research Paper Volume 12, Issue 21 pp 21355-21375
Association of folate intake and plasma folate level with the risk of breast cancer: a dose-response meta-analysis of observational studies
Relevance score: 5.5253496Xueting Ren, Peng Xu, Dai Zhang, Kang Liu, Dingli Song, Yi Zheng, Si Yang, Na Li, Qian Hao, Ying Wu, Zhen Zhai, Huafeng Kang, Zhijun Dai
Keywords: breast cancer, risk, folate, dose-response, meta-analysis
Published in Aging on November 4, 2020
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Research Paper Volume 12, Issue 18 pp 18415-18435
Association of vitamin C intake with breast cancer risk and mortality: a meta-analysis of observational studies
Relevance score: 5.5253496Dai Zhang, Peng Xu, Yiche Li, Bajin Wei, Si Yang, Yi Zheng, Lijuan Lyu, Yujiao Deng, Zhen Zhai, Na Li, Nan Wang, Jun Lyu, Zhijun Dai
Keywords: vitamin C, breast cancer risk, survival, meta-analysis
Published in Aging on September 29, 2020
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Research Paper Volume 12, Issue 11 pp 10772-10794
Meta-analysis of the association between nut consumption and the risks of cancer incidence and cancer-specific mortality
Relevance score: 5.944803Dai Zhang, Cong Dai, Linghui Zhou, Yiche Li, Kang Liu, Yu-Jiao Deng, Na Li, Yi Zheng, Qian Hao, Si Yang, Dingli Song, Ying Wu, Zhen Zhai, Shiyi Cao, Zhijun Dai
Keywords: cancer, risk, mortality, nuts, meta-analysis
Published in Aging on June 2, 2020
The process of identification and inclusion of studies.
Overall meta-analyses of the association between nut intake and the risk of cancer. Note: Weights are from the random-effects analysis. Abbreviations: RR, relative risk; CI, confidence interval.
Subgroup analyses of the association between nut intake and specific types of cancer. Note: Weights are from the random-effects analysis. Abbreviations: PC, prostate cancer; EC, esophagus cancer; CRC, colorectal cancer; GC, gastric cancer; PCC, pancreatic cancer; LC, lung cancer; BC, breast cancer; EndC, endometrial cancer; OC, ovarian cancer; LVC, liver cancer, RR, relative risk; CI, confidence interval.
The meta-analysis of the association between nut intake (per 15 g/day) and risk of cancer. Note: Weights are from the random-effects analysis. Abbreviations: RR, relative risk; CI, confidence interval.
Association between nut intake and cancer-specific mortality. Note: Weights are from the random-effects analysis. Abbreviations: OR, odds ratio; CI, confidence interval.
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Research Paper Volume 12, Issue 7 pp 5894-5906
Risk of breast cancer-related death in women with a prior cancer
Relevance score: 5.385024Fei Ji, Ci-Qiu Yang, Xiao-Ling Li, Liu-Lu Zhang, Mei Yang, Jie-Qing Li, Hong-Fei Gao, Teng Zhu, Min-Yi Cheng, Wei-Ping Li, Si-Yan Wu, Ai-Ling Zhong, Kun Wang
Keywords: second primary malignancy, breast cancer, risk factor, survival
Published in Aging on April 6, 2020
Overall survival (OS) of patients with breast cancer as a second primary cancer. (A) OS curves of patients with different types of prior cancer. (B) the percentage of deaths related to breast cancer or prior cancer among patients with different types of prior cancer. For some types of prior cancer, breast cancer resulted in more deaths than the prior cancer.
The association of breast cancer treatment with breast cancer deaths in patients with breast cancer as a second primary cancer. Breast cancer treatment was associated with decreased breast cancer deaths in these patients.
Ratio of breast cancer deaths to prior cancer deaths among patients with different types of prior cancer. Patients with prior gastrointestinal cancer, melanoma, and urinary tract cancer were more likely to die of breast cancer when they had high-grade or stage cT3–T4/N0/M0 breast cancer, but were more likely to die of prior cancer when they had low-grade and stage cT1–2/N0/M0 breast cancer.
Kaplan-Meier survival curves of patients with breast cancer as the second primary cancer or the prior cancer. (A) BCSS was significantly shorter in patients with breast cancer as the second primary cancer than in those with breast cancer as the prior cancer in the entire cohort. (B) OS was significantly shorter in patients with breast cancer as the second primary cancer than in those with breast cancer as the prior cancer in the entire cohort. After PSM, both BCSS (C) and OS (D) were significantly lower in patients with breast cancer as the second primary cancer than in those with breast cancer as the prior cancer.
Kaplan-Meier survival curves of patients with breast cancer as the second primary cancer or the prior cancer and with different hormone receptor statuses. Breast cancer as the second primary cancer was significantly associated with shorter BCSS and OS in hormone receptor-positive subgroups (A–H).
Forest plot of the hazard ratios for survival of patients with breast cancer as the second primary cancer or the prior cancer. Breast cancer as the second primary cancer was associated with short BCSS (A) and OS (B) in most of the subgroups.
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Research Paper Volume 11, Issue 24 pp 12708-12732
Vitamin D intake, blood vitamin D levels, and the risk of breast cancer: a dose-response meta-analysis of observational studies
Relevance score: 5.1081414Dingli Song, Yujiao Deng, Kang Liu, Linghui Zhou, Na Li, Yi Zheng, Qian Hao, Si Yang, Ying Wu, Zhen Zhai, Hongtao Li, Zhijun Dai
Keywords: vitamin D, dose-response, breast cancer risk, menopause, meta-analysis
Published in Aging on December 28, 2019
Flowchart of included studies for the meta-analysis.
Forest plot of meta-analysis of the association between vitamin D intake increment (per 400IU/d) and breast cancer risk. Abbreviations: OR, odds ratio; CI, confidence interval.
Forest plot of meta-analysis of the association between blood vitamin D increment (per 5nmol/L) and breast cancer risk. Abbreviations: OR, odds ratio; CI, confidence interval.
Dose–response meta-analysis of blood vitamin D and breast cancer risk (linear and nonlinear models).
Dose-response meta-analysis of blood vitamin D and breast cancer risk stratified by menopausal status (linear and nonlinear models). Note: (A) Premenopause; (B) Postmenopause.
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Research Perspective Volume 11, Issue 4 pp 1305-1316
Towards a more precise and individualized assessment of breast cancer risk
Relevance score: 5.643084Marie E. Wood, Nicholas H. Farina, Thomas P. Ahern, Melissa E. Cuke, Janet L. Stein, Gary S. Stein, Jane B. Lian
Keywords: breast cancer risk, precision risk assessment, biomarkers, circulating miRNA
Published in Aging on February 20, 2019
Development of a predictive miRNA signature for breast cancer risk among high-risk women. The predictive ability of A) the 6-miRNA risk signature and B) each individual C-miRNA was assessed by ROC curve and AUC based on calculated risk score. The combined expression of the 6 C-miRNAs discriminate cases from controls with increased accuracy and precision than any single miRNA. 95% confidence intervals (CI) are indicated by gray area around each curve. Modified from our 2017 Oncotarget publication [104].
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Research Paper Volume 10, Issue 5 pp 1073-1088
XPG rs17655 G>C polymorphism associated with cancer risk: evidence from 60 studies
Relevance score: 5.339801Jie Zhao, Shanshan Chen, Haixia Zhou, Ting Zhang, Yang Liu, Jing He, Jinhong Zhu, Jichen Ruan
Keywords: XPG, rs17655, polymorphism, cancer risk, meta-analysis
Published in Aging on May 20, 2018
Flowchart of included publications.
Forest plot for the association between the XPG rs17655 G>C polymorphism and overall cancer risk under the dominant model (CG/CC vs. GG). For each publication, the estimation of OR and its 95% CI was plotted with a box and a horizontal line. The diamonds represented the pooled ORs and 95% CIs.
Funnel plot for the association between XPG gene rs17655 G>C polymorphism and overall cancer risk under the dominant model (CG/CC vs. GG).
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Research Paper Volume 10, Issue 2 pp 266-277
Four common polymorphisms of BRIP1 (rs2048718, rs4988344, rs4986764, and rs6504074) and cancer risk: evidence from 13,716 cancer patients and 15,590 cancer-free controls
Relevance score: 6.6136904Di Liu, Yi Zheng, Meng Wang, Yujiao Deng, Shuai Lin, Linghui Zhou, Pengtao Yang, Cong Dai, Peng Xu, Qian Hao, Dingli Song, Huafeng Kang, Zhijun Dai
Keywords: BRIP1, polymorphism, cancer risk, meta-analysis
Published in Aging on February 16, 2018
The flow diagram of the meta-analysis. CNKI: China National Knowledge Infrastructure.
Forest plot of OR with 95%CI for the BRIP1 polymorphisms with cancer risk under dominant model rs2048718. CI: confidence interval, OR: odds ratio.
Stratified analysis based on ethnicity for the association between BRIP1 rs4986764 polymorphism and cancer risk using dominant model. (A) based on ethnicity; (B) based on cancer type. CI: confidence interval, OR: odds ratio.
Funnel plots of publication bias. (A) rs2048718; (B) rs4988344; (C) rs4986764; (D) rs6504074.
Sensitivity analysis of the associations between rs4986764 polymorphisms and cancer risk.
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Research Paper pp undefined-undefined
Characterization of tumor endothelial cells (TEC) in gastric cancer and development of a TEC-based risk signature using single-cell RNA-seq and bulk RNA-seq data
Relevance score: 5.98599Meng Fan, Xiaofei Xu, Yu Hu
Keywords: tumor endothelial cells, gastric cancer, risk signature, immunotherapy
Published in Aging on Invalid Date
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Research Paper pp undefined-undefined
Associations of PD-1 and PD-L1 gene polymorphisms with cancer risk: a meta-analysis based on 50 studies
Relevance score: 5.1428895Maoquan Yang, Yan Liu, Shuangshuang Zheng, Peizhen Geng, Tianhao He, Linan Lu, Yikuan Feng, Qiqi Jiang
Keywords: PD-1, PD-L1, polymorphism, cancer risk, meta-analysis
Published in Aging on Invalid Date
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Research Paper pp undefined-undefined
Eosinophils and drugs for eosinophilia are associated with the risk of colorectal cancer: A Mendelian randomization study
Relevance score: 5.1428895Yuan-Yuan Wang, Zhi-Han Jia, Qing-Jun Wang, Zhi-Tu Zhu
Keywords: eosinophils, cancer risk, colorectal cancer, Mendelian randomization, pan-cancer
Published in Aging on Invalid Date